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The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKa/mTOR pathway in vitro and in vivo
Telmisartan, a widely used antihypertensive drug, is an angiotensin II type 1 (AT1) receptor blocker (ARB). This drug inhibits cancer cell proliferation, but the underlying mechanisms in various cancers, including esophageal cancer, remain unknown. The aim of the present study was to evaluate the ef...
Autores principales: | Fujihara, Shintaro, Morishita, Asahiro, Ogawa, Kana, Tadokoro, Tomoko, Chiyo, Taiga, Kato, Kiyohito, Kobara, Hideki, Mori, Hirohito, Iwama, Hisakazu, Masaki, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352420/ https://www.ncbi.nlm.nih.gov/pubmed/28052030 http://dx.doi.org/10.18632/oncotarget.14345 |
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