Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages

Stromal cells in the tumor microenvironment (TME) closely interact with tumor cells and affect tumor cell behavior in diverse manners. We herein investigated the mechanisms by which cancer-associated fibroblasts (CAFs) affect the functional polarization of tumor-associated macrophages (TAMs) in oral...

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Detalles Bibliográficos
Autores principales: Takahashi, Hideyuki, Sakakura, Koichi, Kudo, Takeshi, Toyoda, Minoru, Kaira, Kyoichi, Oyama, Tetsunari, Chikamatsu, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352428/
https://www.ncbi.nlm.nih.gov/pubmed/28052009
http://dx.doi.org/10.18632/oncotarget.14374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352428/
https://www.ncbi.nlm.nih.gov/pubmed/28052009
http://dx.doi.org/10.18632/oncotarget.14374

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