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Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages
Stromal cells in the tumor microenvironment (TME) closely interact with tumor cells and affect tumor cell behavior in diverse manners. We herein investigated the mechanisms by which cancer-associated fibroblasts (CAFs) affect the functional polarization of tumor-associated macrophages (TAMs) in oral...
Autores principales: | Takahashi, Hideyuki, Sakakura, Koichi, Kudo, Takeshi, Toyoda, Minoru, Kaira, Kyoichi, Oyama, Tetsunari, Chikamatsu, Kazuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352428/ https://www.ncbi.nlm.nih.gov/pubmed/28052009 http://dx.doi.org/10.18632/oncotarget.14374 |
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