Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer

In immune cells, CD73 dephosphorylates and converts extracellular AMP into adenosine, which binds the A2A adenosine receptor (A2AR). Blockade of this interaction, which induces an immunosuppressed niche in the tumor microenvironment, represents a potential novel treatment strategy. The clinical sign...

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Detalles Bibliográficos
Autores principales: Inoue, Yusuke, Yoshimura, Katsuhiro, Kurabe, Nobuya, Kahyo, Tomoaki, Kawase, Akikazu, Tanahashi, Masayuki, Ogawa, Hiroshi, Inui, Naoki, Funai, Kazuhito, Shinmura, Kazuya, Niwa, Hiroshi, Suda, Takafumi, Sugimura, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352437/
https://www.ncbi.nlm.nih.gov/pubmed/28060732
http://dx.doi.org/10.18632/oncotarget.14434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352437/
https://www.ncbi.nlm.nih.gov/pubmed/28060732
http://dx.doi.org/10.18632/oncotarget.14434

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