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Improving anticancer drug development begins with cell culture: misinformation perpetrated by the misuse of cytotoxicity assays
The high failure rate of anticancer drug discovery and development has consumed billions of dollars annually. While many explanations have been provided, I believe that misinformation arising from inappropriate cell-based screens has been completely over-looked. Most cell culture experiments are irr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352448/ https://www.ncbi.nlm.nih.gov/pubmed/27750219 http://dx.doi.org/10.18632/oncotarget.12673 |