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The role of p53 in cancer drug resistance and targeted chemotherapy

Cancer has long been a grievous disease complicated by innumerable players aggravating its cure. Many clinical studies demonstrated the prognostic relevance of the tumor suppressor protein p53 for many human tumor types. Overexpression of mutated p53 with reduced or abolished function is often conne...

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Detalles Bibliográficos
Autores principales: Hientz, Karin, Mohr, André, Bhakta-Guha, Dipita, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352454/
https://www.ncbi.nlm.nih.gov/pubmed/27888811
http://dx.doi.org/10.18632/oncotarget.13475