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Next-generation sequencing of human opioid receptor genes based on a custom AmpliSeq™ library and ion torrent personal genome machine

BACKGROUND: The opioid system is involved in the control of pain, reward, addictive behaviors and vegetative effects. Opioids exert their pharmacological actions through the agonistic binding at opioid receptors and variation in the coding genes has been found to modulate opioid receptor expression...

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Detalles Bibliográficos
Autores principales: Kringel, Dario, Lötsch, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352731/
https://www.ncbi.nlm.nih.gov/pubmed/27725223
http://dx.doi.org/10.1016/j.cca.2016.10.009