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Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines

PURPOSE: Gastric cancer remains a major health concern, and improvement of the therapeutic options is crucial. Treatment with targeted therapeutics such as the EGFR-targeting antibody cetuximab or the HER2-targeting antibody trastuzumab is either ineffective or moderately effective in this disease,...

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Detalles Bibliográficos
Autores principales: Kneissl, Julia, Hartmann, Anja, Pfarr, Nicole, Erlmeier, Franziska, Lorber, Thomas, Keller, Simone, Zwingenberger, Gwen, Weichert, Wilko, Luber, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352771/
https://www.ncbi.nlm.nih.gov/pubmed/27933395
http://dx.doi.org/10.1007/s00432-016-2308-z