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Neutron activation increases activity of ruthenium-based complexes and induces cell death in glioma cells independent of p53 tumor suppressor gene

Novel metal complexes have received great attention in the last decades due to their potential anticancer activity. Notably, ruthenium-based complexes have emerged as good alternative to the currently used platinum-based drugs for cancer therapy, providing less toxicity and side effects to patients....

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Detalles Bibliográficos
Autores principales: Montel, Aline Monezi, dos Santos, Raquel Gouvêa, da Costa, Pryscila Rodrigues, Silveira-Lacerda, Elisângela de Paula, Batista, Alzir Azevedo, dos Santos, Wagner Gouvêa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352776/
https://www.ncbi.nlm.nih.gov/pubmed/28258507
http://dx.doi.org/10.1007/s10534-017-0006-1