Intramyocardial Injection of Recombinant Adeno-Associated Viral Vector Coexpressing PR39/Adrenomedullin Enhances Angiogenesis and Reduces Apoptosis in a Rat Myocardial Infarction Model

Cotransfer of angiogenic and antiapoptotic genes could be the basis of new gene therapy strategies for myocardial infarction. In this study, rAAV-PR39-ADM, coexpressing antimicrobial peptide (PR39) and adrenomedullin (ADM), was designed with the mediation of recombinant adeno-associated virus. In vi...

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Detalles Bibliográficos
Autores principales: An, Rui, Xi, Cong, Xu, Jian, Liu, Ying, Zhang, Shumiao, Wang, Yuemin, Hao, Yuewen, Sun, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352904/
https://www.ncbi.nlm.nih.gov/pubmed/28348718
http://dx.doi.org/10.1155/2017/1271670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352904/
https://www.ncbi.nlm.nih.gov/pubmed/28348718
http://dx.doi.org/10.1155/2017/1271670

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