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Calretinin and Neuropeptide Y interneurons are differentially altered in the motor cortex of the SOD1(G93A) mouse model of ALS

Increasing evidence indicates an excitatory/inhibitory imbalance may have a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS). Impaired inhibitory circuitry is consistently reported in the motor cortex of both familial and sporadic patients, closely associated with cortical hy...

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Detalles Bibliográficos
Autores principales: Clark, Rosemary M., Blizzard, Catherine A., Young, Kaylene M., King, Anna E., Dickson, Tracey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353592/
https://www.ncbi.nlm.nih.gov/pubmed/28294153
http://dx.doi.org/10.1038/srep44461