EGFR/ARF6 regulation of Hh signalling stimulates oncogenic Ras tumour overgrowth

Multiple signalling events interact in cancer cells. Oncogenic Ras cooperates with Egfr, which cannot be explained by the canonical signalling paradigm. In turn, Egfr cooperates with Hedgehog signalling. How oncogenic Ras elicits and integrates Egfr and Hedgehog signals to drive overgrowth remains u...

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Detalles Bibliográficos
Autores principales: Chabu, Chiswili, Li, Da-Ming, Xu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353614/
https://www.ncbi.nlm.nih.gov/pubmed/28281543
http://dx.doi.org/10.1038/ncomms14688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353614/
https://www.ncbi.nlm.nih.gov/pubmed/28281543
http://dx.doi.org/10.1038/ncomms14688

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