Imbalance between TNFα and progranulin contributes to memory impairment and anxiety in sleep-deprived mice

Sleep disorder is becoming a widespread problem in current society, and is associated with impaired cognition and emotional disorders. Progranulin (PGRN), also known as granulin epithelin precursor, promotes neurite outgrowth and cell survival, and is encoded by the GRN gene. It is a tumor necrosis...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Li, Yu-jiao, Feng, Dan, Zhang, Peng, Wang, Ya-tao, Li, Xiang, Liu, Shui-bing, Wu, Yu-mei, Zhao, Ming-gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353617/
https://www.ncbi.nlm.nih.gov/pubmed/28300056
http://dx.doi.org/10.1038/srep43594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353617/
https://www.ncbi.nlm.nih.gov/pubmed/28300056
http://dx.doi.org/10.1038/srep43594

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