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Imbalance between TNFα and progranulin contributes to memory impairment and anxiety in sleep-deprived mice
Sleep disorder is becoming a widespread problem in current society, and is associated with impaired cognition and emotional disorders. Progranulin (PGRN), also known as granulin epithelin precursor, promotes neurite outgrowth and cell survival, and is encoded by the GRN gene. It is a tumor necrosis...
Autores principales: | Zhang, Kun, Li, Yu-jiao, Feng, Dan, Zhang, Peng, Wang, Ya-tao, Li, Xiang, Liu, Shui-bing, Wu, Yu-mei, Zhao, Ming-gao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353617/ https://www.ncbi.nlm.nih.gov/pubmed/28300056 http://dx.doi.org/10.1038/srep43594 |
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