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Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea

An adverse role for obstructive sleep apnea (OSA) in cancer epidemiology and outcomes has recently emerged from clinical and animal studies. In animals, intermittent hypoxia (IH) mimicking OSA promotes tumor malignancy both directly and via host immune alterations. We hypothesized that IH could pote...

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Detalles Bibliográficos
Autores principales: Campillo, Noelia, Torres, Marta, Vilaseca, Antoni, Nonaka, Paula Naomi, Gozal, David, Roca-Ferrer, Jordi, Picado, César, Montserrat, Josep Maria, Farré, Ramon, Navajas, Daniel, Almendros, Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353645/
https://www.ncbi.nlm.nih.gov/pubmed/28300223
http://dx.doi.org/10.1038/srep44693