The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic β-cell injury

Lipotoxicity has been implicated in pancreatic β-cell dysfunction in type 2 diabetes, but the exact mechanisms remain unknown. The current study explored the role of the endoplasmic reticulum (ER) stress pathway in cholesterol-induced lipotoxicity. Two different insulinoma cell lines were treated wi...

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Detalles Bibliográficos
Autores principales: Kong, Fei-Juan, Wu, Jia-Hua, Sun, Shui-Ya, Zhou, Jia-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353658/
https://www.ncbi.nlm.nih.gov/pubmed/28294183
http://dx.doi.org/10.1038/srep44746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353658/
https://www.ncbi.nlm.nih.gov/pubmed/28294183
http://dx.doi.org/10.1038/srep44746

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