Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

Remarkably little is known about how intracellular pathogens exit the host cell in order to infect new hosts. Pathogenic chlamydiae egress by first rupturing their replicative niche (the inclusion) before rapidly lysing the host cell. Here we apply a laser ablation strategy to specifically disrupt t...

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Detalles Bibliográficos
Autores principales: Kerr, Markus C., Gomez, Guillermo A., Ferguson, Charles, Tanzer, Maria C., Murphy, James M., Yap, Alpha S., Parton, Robert G., Huston, Wilhelmina M., Teasdale, Rohan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353685/
https://www.ncbi.nlm.nih.gov/pubmed/28281536
http://dx.doi.org/10.1038/ncomms14729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353685/
https://www.ncbi.nlm.nih.gov/pubmed/28281536
http://dx.doi.org/10.1038/ncomms14729

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