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In vitro drug testing based on contractile activity of C2C12 cells in an epigenetic drug model

Skeletal muscle tissue engineering holds great promise for pharmacological studies. Herein, we demonstrated an in vitro drug testing system using tissue-engineered skeletal muscle constructs. In response to epigenetic drugs, myotube differentiation of C2C12 myoblast cells was promoted in two-dimensi...

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Detalles Bibliográficos
Autores principales: Ikeda, Kazushi, Ito, Akira, Imada, Ryusuke, Sato, Masanori, Kawabe, Yoshinori, Kamihira, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353687/
https://www.ncbi.nlm.nih.gov/pubmed/28300163
http://dx.doi.org/10.1038/srep44570