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Both Drosophila matrix metalloproteinases have released and membrane-tethered forms but have different substrates

Matrix metalloproteinases (MMPs) are extracellular proteases that can cleave extracellular matrix and alter signaling pathways. They have been implicated in many disease states, but it has been difficult to understand the contribution of individual MMPs, as there are over 20 MMPs in vertebrates. The...

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Detalles Bibliográficos
Autores principales: LaFever, Kimberly S., Wang, Xiaoxi, Page-McCaw, Patrick, Bhave, Gautam, Page-McCaw, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353688/
https://www.ncbi.nlm.nih.gov/pubmed/28300207
http://dx.doi.org/10.1038/srep44560