Renal Medulla is More Sensitive to Cisplatin than Cortex Revealed by Untargeted Mass Spectrometry-Based Metabolomics in Rats

Nephrotoxicity has long been the most severe and life-threatening side-effect of cisplatin, whose anticancer effect is therefore restricted. Previous pathological studies have shown that both renal cortex and medulla could be injured by cisplatin. Our TUNEL (terminal deoxynucleotidyl transferase-med...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Pei, Chen, Jia-Qing, Huang, Wan-Qiu, Li, Wei, Huang, Yin, Zhang, Zun-Jian, Xu, Feng-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353697/
https://www.ncbi.nlm.nih.gov/pubmed/28300186
http://dx.doi.org/10.1038/srep44804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353697/
https://www.ncbi.nlm.nih.gov/pubmed/28300186
http://dx.doi.org/10.1038/srep44804

Ejemplares similares