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Renal Medulla is More Sensitive to Cisplatin than Cortex Revealed by Untargeted Mass Spectrometry-Based Metabolomics in Rats

Nephrotoxicity has long been the most severe and life-threatening side-effect of cisplatin, whose anticancer effect is therefore restricted. Previous pathological studies have shown that both renal cortex and medulla could be injured by cisplatin. Our TUNEL (terminal deoxynucleotidyl transferase-med...

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Detalles Bibliográficos
Autores principales:	Zhang, Pei, Chen, Jia-Qing, Huang, Wan-Qiu, Li, Wei, Huang, Yin, Zhang, Zun-Jian, Xu, Feng-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353697/ https://www.ncbi.nlm.nih.gov/pubmed/28300186 http://dx.doi.org/10.1038/srep44804

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