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Theory of optimal balance predicts and explains the amplitude and decay time of synaptic inhibition

Synaptic inhibition counterbalances excitation, but it is not known what constitutes optimal inhibition. We previously proposed that perfect balance is achieved when the peak of an excitatory postsynaptic potential (EPSP) is exactly at spike threshold, so that the slightest variation in excitation d...

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Detalles Bibliográficos
Autores principales: Kim, Jaekyung K., Fiorillo, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353699/
https://www.ncbi.nlm.nih.gov/pubmed/28281523
http://dx.doi.org/10.1038/ncomms14566