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Effect of modulation of PPAR-γ activity on Kupffer cells M1/M2 polarization in the development of non-alcoholic fatty liver disease

Abnormal lipid-mediated hepatic inflammatory-immune dysfunction and chronic low grade inflammation play an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Macrophage polarization is an important mechanism for the regulation of inflammatory response. Since PPAR-γ has...

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Detalles Bibliográficos
Autores principales: Luo, Wenjing, Xu, Qinyu, Wang, Qi, Wu, Huimin, Hua, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353732/
https://www.ncbi.nlm.nih.gov/pubmed/28300213
http://dx.doi.org/10.1038/srep44612