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Optimization of the Expression of DT386-BR2 Fusion Protein in Escherichia coli using Response Surface Methodology
BACKGROUND: The aim of this study was to determine the best condition for the production of DT386-BR2 fusion protein, an immunotoxin consisting of catalytic and translocation domains of diphtheria toxin fused to BR2, a cancer specific cell penetrating peptide, for targeted eradication of cancer cell...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353773/ https://www.ncbi.nlm.nih.gov/pubmed/28349025 http://dx.doi.org/10.4103/2277-9175.201334 |