Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia

BACKGROUND: To understand the changes of gene regulation in carcinogenesis, we explored signals of DNA methylation – a stable epigenetic mark of gene regulatory elements — and designed a computational model to profile loss and gain of regulatory elements (REs) during carcinogenesis. We also utilized...

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Detalles Bibliográficos
Autores principales: Huang, Di, Ovcharenko, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353786/
https://www.ncbi.nlm.nih.gov/pubmed/28302063
http://dx.doi.org/10.1186/s12864-017-3617-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353786/
https://www.ncbi.nlm.nih.gov/pubmed/28302063
http://dx.doi.org/10.1186/s12864-017-3617-6

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