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Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies

BACKGROUND: Transcriptional reprogramming is a fundamental process of living cells in order to adapt to environmental and endogenous cues. In order to allow flexible and timely control over gene expression without the interference of native gene expression machinery, a large number of studies have f...

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Detalles Bibliográficos
Autores principales: Jensen, Emil D., Ferreira, Raphael, Jakočiūnas, Tadas, Arsovska, Dushica, Zhang, Jie, Ding, Ling, Smith, Justin D., David, Florian, Nielsen, Jens, Jensen, Michael K., Keasling, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353793/
https://www.ncbi.nlm.nih.gov/pubmed/28298224
http://dx.doi.org/10.1186/s12934-017-0664-2