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Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies
BACKGROUND: Transcriptional reprogramming is a fundamental process of living cells in order to adapt to environmental and endogenous cues. In order to allow flexible and timely control over gene expression without the interference of native gene expression machinery, a large number of studies have f...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353793/ https://www.ncbi.nlm.nih.gov/pubmed/28298224 http://dx.doi.org/10.1186/s12934-017-0664-2 |