Elutriated lymphocytes for manufacturing chimeric antigen receptor T cells

BACKGROUND: Clinical trials of Chimeric Antigen Receptor (CAR) T cells manufactured from autologous peripheral blood mononuclear cell (PBMC) concentrates for the treatment of hematologic malignancies have been promising, but CAR T cell yields have been variable. This variability is due in part to th...

Descripción completa

Detalles Bibliográficos
Autores principales: Stroncek, David F., Lee, Daniel W., Ren, Jiaqiang, Sabatino, Marianna, Highfill, Steven, Khuu, Hanh, Shah, Nirali N., Kaplan, Rosandra N., Fry, Terry J., Mackall, Crystal L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353875/
https://www.ncbi.nlm.nih.gov/pubmed/28298232
http://dx.doi.org/10.1186/s12967-017-1160-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353875/
https://www.ncbi.nlm.nih.gov/pubmed/28298232
http://dx.doi.org/10.1186/s12967-017-1160-5

Ejemplares similares