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Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis

Tissue immunosurveillance is an important mechanism to prevent cancer. Skin treatment with the carcinogen 7,12-dimethylbenz(a)anthracene (DMBA), followed by the tumor promoter 12-O-tetra-decanoyl-phorbol-13-acetate (TPA), is an established murine model for squamous cell carcinoma (SCC). However, the...

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Detalles Bibliográficos
Autores principales: Ortner, Daniela, Tripp, Christoph H., Komenda, Kerstin, Dubrac, Sandrine, Zelger, Bernhard, Hermann, Martin, Doppler, Wolfgang, Tymoszuk, Piotr Z., Boon, Louis, Clausen, Björn E., Stoitzner, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353916/
https://www.ncbi.nlm.nih.gov/pubmed/28344868
http://dx.doi.org/10.1080/2162402X.2016.1260215