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Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast
BACKGROUND: Kinases and phosphatases (KP) form complex self-regulating networks essential for cellular signal processing. In spite of having a wealth of data about interactions among KPs and their substrates, we have very limited models of the structures of the directed networks they form and conseq...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353956/ https://www.ncbi.nlm.nih.gov/pubmed/28298210 http://dx.doi.org/10.1186/s12918-017-0418-0 |