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Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF

Mast cells are accumulated in advanced chronic obstructive pulmonary disease (COPD), and interleukin (IL)-17 signaling plays a role in disease progression. The expression, localization and functional relevance of IL-17 receptor (R)A and IL-17RC was explored in COPD by immunodetection, and functional...

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Detalles Bibliográficos
Autores principales: Roos, Abraham B., Mori, Michiko, Gura, Harpreet K., Lorentz, Axel, Bjermer, Leif, Hoffmann, Hans Jürgen, Erjefält, Jonas S., Stampfli, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353957/
https://www.ncbi.nlm.nih.gov/pubmed/28298222
http://dx.doi.org/10.1186/s12931-017-0534-9