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Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF
Mast cells are accumulated in advanced chronic obstructive pulmonary disease (COPD), and interleukin (IL)-17 signaling plays a role in disease progression. The expression, localization and functional relevance of IL-17 receptor (R)A and IL-17RC was explored in COPD by immunodetection, and functional...
Autores principales: | Roos, Abraham B., Mori, Michiko, Gura, Harpreet K., Lorentz, Axel, Bjermer, Leif, Hoffmann, Hans Jürgen, Erjefält, Jonas S., Stampfli, Martin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353957/ https://www.ncbi.nlm.nih.gov/pubmed/28298222 http://dx.doi.org/10.1186/s12931-017-0534-9 |
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