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Secreted phospholipase A2 of Clonorchis sinensis activates hepatic stellate cells through a pathway involving JNK signalling

BACKGROUND: Secreted phospholipase A2 (sPLA2) is a protein secreted by Clonorchis sinensis and is a component of excretory and secretory products (CsESPs). Phospholipase A2 is well known for its role in liver fibrosis and inhibition of tumour cells. The JNK signalling pathway is involved in hepatic...

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Detalles Bibliográficos
Autores principales: Wu, Yinjuan, Li, Ye, Shang, Mei, Jian, Yu, Wang, Caiqin, Bardeesi, Adham Sameer A., Li, Zhaolei, Chen, Tingjin, Zhao, Lu, Zhou, Lina, He, Ai, Huang, Yan, Lv, Zhiyue, Yu, Xinbing, Li, Xuerong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353963/
https://www.ncbi.nlm.nih.gov/pubmed/28302166
http://dx.doi.org/10.1186/s13071-017-2082-z