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The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination
Epithelial to mesenchymal transition is a common event during tumour dissemination. However, direct epithelial to amoeboid transition has not been characterized to date. Here we provide evidence that cells from hepatocellular carcinoma (HCC), a highly metastatic cancer, undergo epithelial to amoeboi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354266/ https://www.ncbi.nlm.nih.gov/pubmed/27941881 http://dx.doi.org/10.1038/onc.2016.454 |