The structure, dynamics and selectivity profile of a Na(V)1.7 potency-optimised huwentoxin-IV variant

Venom-derived peptides have attracted much attention as potential lead molecules for pharmaceutical development. A well-known example is Huwentoxin-IV (HwTx-IV), a peptide toxin isolated from the venom of the Chinese bird-eating spider Haplopelma schmitdi. HwTx-IV was identified as a potent blocker...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina, Mobli, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354290/
https://www.ncbi.nlm.nih.gov/pubmed/28301520
http://dx.doi.org/10.1371/journal.pone.0173551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354290/
https://www.ncbi.nlm.nih.gov/pubmed/28301520
http://dx.doi.org/10.1371/journal.pone.0173551

Ejemplares similares