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Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2
The anti-apoptotic Bcl-2 family protein myeloid cell leukemia-1 (Mcl-1) plays an important role in breast cancer cell survival and chemoresistance. We have previously shown that knockdown of the 40S ribosomal protein S6 kinase-2 (S6K2), which acts downstream of the mechanistic target of rapamycin co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354308/ https://www.ncbi.nlm.nih.gov/pubmed/28301598 http://dx.doi.org/10.1371/journal.pone.0173854 |