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Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2

The anti-apoptotic Bcl-2 family protein myeloid cell leukemia-1 (Mcl-1) plays an important role in breast cancer cell survival and chemoresistance. We have previously shown that knockdown of the 40S ribosomal protein S6 kinase-2 (S6K2), which acts downstream of the mechanistic target of rapamycin co...

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Detalles Bibliográficos
Autores principales:	Basu, Alakananda, Sridharan, Savitha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354308/ https://www.ncbi.nlm.nih.gov/pubmed/28301598 http://dx.doi.org/10.1371/journal.pone.0173854

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