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Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats

Foetal midbrain progenitors have been shown to survive, give rise to different classes of dopamine neurons and integrate into the host brain alleviating Parkinsonian symptoms following transplantation in patients and animal models of the disease. Dopamine neuron subpopulations in the midbrain, namel...

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Detalles Bibliográficos
Autores principales: Fjodorova, Marija, Torres, Eduardo M, Dunnett, Stephen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354310/
https://www.ncbi.nlm.nih.gov/pubmed/28131726
http://dx.doi.org/10.1016/j.expneurol.2017.01.010