Meiotic failure in cyclin A1-deficient mouse spermatocytes triggers apoptosis through intrinsic and extrinsic signaling pathways and 14-3-3 proteins

Cyclin A1 (Ccna1), a member of the mammalian A type cyclins, is most abundantly expressed in spermatocytes and is essential for spermatogenesis in the mouse. Ccna1- deficient spermatocytes arrest at late meiotic prophase and undergo apoptosis. To further delineate the mechanisms and key factors invo...

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Detalles Bibliográficos
Autores principales: Panigrahi, Sunil K., Manterola, Marcia, Wolgemuth, Debra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354389/
https://www.ncbi.nlm.nih.gov/pubmed/28301569
http://dx.doi.org/10.1371/journal.pone.0173926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354389/
https://www.ncbi.nlm.nih.gov/pubmed/28301569
http://dx.doi.org/10.1371/journal.pone.0173926

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