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Lysosomal adaptation: How cells respond to lysosomotropic compounds
Lysosomes are acidic organelles essential for degradation and cellular homoeostasis and recently lysosomes have been shown as signaling hub to respond to the intra and extracellular changes (e.g. amino acid availability). Compounds including pharmaceutical drugs that are basic and lipophilic will be...
Autores principales: | Lu, Shuyan, Sung, Tae, Lin, Nianwei, Abraham, Robert T., Jessen, Bart A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354416/ https://www.ncbi.nlm.nih.gov/pubmed/28301521 http://dx.doi.org/10.1371/journal.pone.0173771 |
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