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Influence of a pre-stimulation with chronic low-dose UVB on stress response mechanisms in human skin fibroblasts
Exposure to solar ultraviolet type B (UVB), through the induction of cyclobutane pyrimidine dimer (CPD), is the major risk factor for cutaneous cancer. Cells respond to UV-induced CPD by triggering the DNA damage response (DDR) responsible for signaling DNA repair, programmed cell death and cell cyc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354420/ https://www.ncbi.nlm.nih.gov/pubmed/28301513 http://dx.doi.org/10.1371/journal.pone.0173740 |