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Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study

Autism spectrum disorder (ASD) is associated with physiological abnormalities, including abnormal redox and mitochondrial metabolism. Lymphoblastoid cell lines (LCLs) from some children with ASD exhibit increased oxidative stress, decreased glutathione redox capacity, and highly active mitochondria...

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Detalles Bibliográficos
Autores principales: Rose, Shannon, Bennuri, Sirish C., Wynne, Rebecca, Melnyk, Stepan, James, S. Jill, Frye, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354548/
https://www.ncbi.nlm.nih.gov/pubmed/27864377
http://dx.doi.org/10.1096/fj.201601004R