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The many facets of homologous recombination at telomeres

The ends of linear chromosomes are capped by nucleoprotein structures called telomeres. A dysfunctional telomere may resemble a DNA double-strand break (DSB), which is a severe form of DNA damage. The presence of one DSB is sufficient to drive cell cycle arrest and cell death. Therefore cells have e...

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Detalles Bibliográficos
Autores principales: Claussin, Clémence, Chang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354574/
https://www.ncbi.nlm.nih.gov/pubmed/28357308
http://dx.doi.org/10.15698/mic2015.09.224