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DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres

In budding yeast, telomerase and the Cdc13p protein are two key players acting to ensure telomere stability. In the absence of telomerase, cells eventually enter a growth arrest which only few can overcome via a conserved process; such cells are called survivors. Survivors rely on homologous recombi...

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Detalles Bibliográficos
Autores principales: Mersaoui, Sofiane Y., Gravel, Serge, Karpov, Victor, Wellinger, Raymund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354583/
https://www.ncbi.nlm.nih.gov/pubmed/28357265
http://dx.doi.org/10.15698/mic2015.10.229