Ergosterone-coupled Triazol molecules trigger mitochondrial dysfunction, oxidative stress, and acidocalcisomal Ca(2+) release in Leishmania mexicana promastigotes

The protozoan parasite Leishmania causes a variety of sicknesses with different clinical manifestations known as leishmaniasis. The chemotherapy currently in use is not adequate because of their side effects, resistance occurrence, and recurrences. Investigations looking for new targets or new activ...

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Detalles Bibliográficos
Autores principales: Figarella, K, Marsiccobetre, S, Arocha, I, Colina, W, Hasegawa, M, Rodriguez, M, Rodriguez-Acosta, A, Duszenko, M, Benaim, G, Uzcategui, NL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354587/
https://www.ncbi.nlm.nih.gov/pubmed/28357313
http://dx.doi.org/10.15698/mic2016.01.471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354587/
https://www.ncbi.nlm.nih.gov/pubmed/28357313
http://dx.doi.org/10.15698/mic2016.01.471

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