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Yeast proteinopathy models: a robust tool for deciphering the basis of neurodegeneration

Protein quality control or proteostasis is an essential determinant of basic cell health and aging. Eukaryotic cells have evolved a number of proteostatic mechanisms to ensure that proteins retain functional conformation, or are rapidly degraded when proteins misfold or self-aggregate. Disruption of...

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Detalles Bibliográficos
Autores principales: Shrestha, Amit, Megeney, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354604/
https://www.ncbi.nlm.nih.gov/pubmed/28357271
http://dx.doi.org/10.15698/mic2015.12.243