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A central role for TOR signalling in a yeast model for juvenile CLN3 disease

Yeasts provide an excellent genetically tractable eukaryotic system for investigating the function of genes in their biological context, and are especially relevant for those conserved genes that cause disease. We study the role of btn1, the orthologue of a human gene that underlies an early onset n...

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Detalles Bibliográficos
Autores principales: Bond, Michael E., Brown, Rachel, Rallis, Charalampos, Bähler, Jürg, Mole, Sara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354605/
https://www.ncbi.nlm.nih.gov/pubmed/28357272
http://dx.doi.org/10.15698/mic2015.12.241