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COX-2/mPGES-1/PGE(2) cascade activation mediates uric acid-induced mesangial cell proliferation

Hyperuricemia is not only the main feature of gout but also a cause of gout-related organ injuries including glomerular hypertrophy and sclerosis. Uric acid (UA) has been proven to directly cause mesangial cell (MC) proliferation with elusive mechanisms. The present study was undertaken to examined...

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Detalles Bibliográficos
Autores principales: Li, Shuzhen, Sun, Zhenzhen, Zhang, Yue, Ruan, Yuan, Chen, Qiuxia, Gong, Wei, Yu, Jing, Xia, Weiwei, He, John Ci-Jiang, Huang, Songming, Zhang, Aihua, Ding, Guixia, Jia, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354651/
https://www.ncbi.nlm.nih.gov/pubmed/28052039
http://dx.doi.org/10.18632/oncotarget.14363