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COX-2/mPGES-1/PGE(2) cascade activation mediates uric acid-induced mesangial cell proliferation
Hyperuricemia is not only the main feature of gout but also a cause of gout-related organ injuries including glomerular hypertrophy and sclerosis. Uric acid (UA) has been proven to directly cause mesangial cell (MC) proliferation with elusive mechanisms. The present study was undertaken to examined...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354651/ https://www.ncbi.nlm.nih.gov/pubmed/28052039 http://dx.doi.org/10.18632/oncotarget.14363 |