EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions

Multiple Myeloma (MM) is a plasma cell tumor localized to the bone marrow (BM). Despite the fact that current treatment strategies have improved patients' median survival time, MM remains incurable. Epigenetic aberrations are emerging as important players in tumorigenesis making them attractive...

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Detalles Bibliográficos
Autores principales: Alzrigat, Mohammad, Párraga, Alba Atienza, Agarwal, Prasoon, Zureigat, Hadil, Österborg, Anders, Nahi, Hareth, Ma, Anqi, Jin, Jian, Nilsson, Kenneth, Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354653/
https://www.ncbi.nlm.nih.gov/pubmed/28052011
http://dx.doi.org/10.18632/oncotarget.14378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354653/
https://www.ncbi.nlm.nih.gov/pubmed/28052011
http://dx.doi.org/10.18632/oncotarget.14378

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