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Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM

Radiation therapy is a mainstay of cancer treatment, yet the molecular determinants of clinical response are poorly understood. We identified exceptional responders to radiotherapy based on clinical response, and investigated the associated tumor sequencing data in order to identify additional patie...

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Detalles Bibliográficos
Autores principales: Ma, Jennifer, Setton, Jeremy, Morris, Luc, Carrillo Albornoz, Pedro Blecua, Barker, Christopher, Lok, Benjamin H., Sherman, Eric, Katabi, Nora, Beal, Kathryn, Ganly, Ian, Powell, Simon N., Lee, Nancy, Chan, Timothy A., Riaz, Nadeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354661/
https://www.ncbi.nlm.nih.gov/pubmed/28055970
http://dx.doi.org/10.18632/oncotarget.14400