Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures

Progression of prostate cancer (PC) to castration-recurrent growth (CRPC) remains dependent on sustained expression and transcriptional activity of the androgen receptor (AR). A major mechanism contributing to CRPC progression is through the direct phosphorylation and activation of AR by Src-family...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Indranil, Wang, Jianmin, Qin, Maochun, Gao, Lingqiu, Holtz, Renae, Vessella, Robert L., Leach, Robert W., Gelman, Irwin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354662/
https://www.ncbi.nlm.nih.gov/pubmed/28055971
http://dx.doi.org/10.18632/oncotarget.14401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354662/
https://www.ncbi.nlm.nih.gov/pubmed/28055971
http://dx.doi.org/10.18632/oncotarget.14401

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